Proportion of DNA gyrase mutants among quinolone-resistant strains of Pseudomonas aeruginosa.

نویسندگان

  • H Yoshida
  • M Nakamura
  • M Bogaki
  • S Nakamura
چکیده

The proportion of DNA gyrase mutants among quinolone-resistant strains of Pseudomonas aeruginosa was examined by introducing the cloned wild-type Escherichia coli gyrA and gyrB genes. Of 101 spontaneous mutants of P. aeruginosa PAO505, 33 (33%) were found to have gyrA mutations. Among 17 clinical isolates, 12 (71%) had gyrA mutations and 1 (6%) had a gyrB mutation.

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منابع مشابه

Reduction of the fitness burden of quinolone resistance in Pseudomonas aeruginosa.

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Study of Mutations in the DNA gyrase gyrA Gene of Escherichia coli

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 34 6  شماره 

صفحات  -

تاریخ انتشار 1990